This supplement to The American Journal of Managed Care looks at emerging evidence in NSAID pharmacology, including the relationship between COX selectivity and NSAID dose, the effect of NSAID dosing ...

Researchers from Kanazawa University find that propionic acid-class NSAIDs are conjugated with CoA by hepatic ACSL1, leading to liver toxicity via covalent binding with hepatic proteins Kanazawa, ...

Recent advances in dental therapeutics, pharmacology and toxicology have fundamentally reshaped clinical practice in dentistry. Enhanced understanding of drug mechanisms—from the actions of ...

Liver injury is a rare side effect of nonsteroidal anti-inflammatory drugs (NSAIDs), which are frequently used for daily pain control. This toxicity has been regarded as a "black box" and is mainly ...

Acetaminophen 1000mg, ibuprofen 300mg; per 100mL; soln for IV infusion; preservative-free. Acetaminophen is a non-opiate, non-salicylate analgesic. The precise mechanism of the analgesic properties of ...

Different classes of pain relievers work in different ways. Here’s how to figure out the ideal one for you. Ask Well Different classes of pain relievers work in different ways. Here’s how to figure ...

DEAR PEOPLE’S PHARMACY: I was taking ibuprofen (600 milligrams, two times per day) for arthritis pain, but I had to stop because it was causing renal insufficiency. This had happened before while I ...