Last, he invoked pleiotropic mineralocorticoid effects, such as activation of innate immunity and clearance of alveolar fluid, to support the need to reexamine hydro/fludro. In his study ...

We wanted to see if the new nonsteroidal mineralocorticoid receptor antagonist finerenone had similar effects across the cardio-kidney-metabolic spectrum.” Pabon and colleagues found that ...

Spironolactone inhibits the effects of aldosterone by binding to the mineralocorticoid receptor. Both insulin resistance and obesity have substantial effects on aldosterone action; 7,8 hence ...

The kaliuretic effect of loop diuretics such as furosemide means that hyperkalemia associated with mineralocorticoid-receptor antagonists can generally be avoided by coadministration of furosemide ...