Ivermectin is primarily used in dogs for the prevention and treatment of heartworm disease. The parasitic worm Dirofilaria immitis, living in the heart and pulmonary arteries of dogs, causes this ...

When used as recommended, Simparica Trio is safe and effective for most dogs, including those who are heartworm-positive [1, 2 ... a certain gene mutation that makes them more sensitive to ivermectin, ...