San Francisco 49ers running back Isaac ... role. Guerendo should be off of fantasy radars if injured, but the backup role in San Francisco is one to keep track of all season. Source: Jennifer ...

MADISON, Wis. — When Isaac Guerendo takes the field for warmups Saturday at Camp Randall Stadium, it won't quite mark the one-year anniversary of a fluky foot injury that ended his 2021 season.

MADISON, Wis. — Isaac Guerendo’s last two seasons have probably felt like one, long season. There weren’t many differences between 2019 and 2020 for MADISON, Wis. — Isaac Guerendo’s last ...

So fans can be forgiven for thinking that the decision to trade up for Louisville's Isaac Guerendo will be just the latest in a line of running back draft follies by Shanahan and the 49ers.

Since joining the 49ers, Isaac Guerendo's rise to significant snaps came in the wake of injuries to star running backs ...

Guerendo (foot) was listed as a non-participant on Monday's estimated injury report, Nick Wagoner of ESPN.com reports. Guerendo's first career start Sunday against the Bears was fruitful until he ...

In Week 7, running back Isaac Guerendo and the San Francisco 49ers' rushing attack will square off against the Kansas City Chiefs and their fifth-ranked run defense (88.4 rushing yards allowed per ...