Most studies involving patients with hypovolemic shock used a single 250-mL bolus dose of 7.5% hypertonic saline, with or without dextran.

HTS can also be administered in bolus form to treat acute ICP elevations. ... Cite this: Administering Hypertonic Saline to Patients With Severe Traumatic Brain Injury - Medscape - Jun 01, 2006.

Survival at 28 days was 74.3 percent with hypertonic saline/dextran, ... who received a single bolus [large dose] of hypertonic fluids compared with normal saline in the out-of-hospital setting.

After the infusion of a 250-ml bolus of hypertonic saline (sodium chloride, 3%), the infusion was continued at a rate of 0.15 ml per kilogram of body weight per minute.

Preventative Inhalation of Hypertonic Saline in Infants with Cystic Fibrosis (PRESIS): A Randomized, Double-Blind, Controlled Study. American Journal of Respiratory and Critical Care Medicine ...

The prespecified hypertonic saline–stimulated copeptin cutoff level of more than 4.9 pmol per liter 19 had a 93.2% sensitivity (95% CI, 83.5 to 98.1) and 100% specificity (95% CI, 95.5 to 100.0 ...

All children were randomly assigned to receive inhaled two puffs of 100 µg salbutamol followed by 4 mL of 7% hypertonic saline (n = 56) or 0.9% isotonic saline (n = 60) twice daily for 48 weeks.

Nov. 9, 2018--Babies with cystic fibrosis may breathe better by inhaling hypertonic saline, according to a randomized controlled trial conducted in Germany and published in the American Thoracic ...

Hypertonic-saline-induced abortion is an outdated way to terminate second or third trimester pregnancies. Modern procedures are far more safe and effective.

Researchers at the University of São Paulo (USP) in Brazil have shown that a hypertonic saline solution inhibits replication of SARS-CoV-2, the virus that causes COVID-19, and have elucidated the ...

Babies with cystic fibrosis may breathe better by inhaling hypertonic saline, according to a randomized controlled trial conducted in Germany and published in the American Thoracic Society's ...