HTS can also be administered in bolus form to treat acute ICP elevations. A dose of highly concentrated HTS, such as 30 ml of 23.4% NaCl, is given through a central line over approximately 15 min ...

Am J Health Syst Pharm. 2010;67(22):1920-1928. Due to the high osmolarity of hypertonic saline, infusion through a central line is preferred to minimize phlebitis. Most studies used a 7.5% hypertonic ...

Intravenous administration of isotonic fluids is the standard emergency treatment in the U.S. for patients with severe blood loss, but now bioengineering researchers have reported improved ...

Inhaled hypertonic saline acutely increases mucociliary clearance and, in short-term trials, improves lung function in people with cystic fibrosis. We tested the safety and efficacy of inhaled ...

The role of fluid resuscitation in the treatment of children with shock and life-threatening infections who live in resource-limited settings is not established. We randomly assigned children with ...