Early research shows that editing expanding trinucleotide repeats halts the lengthening process that causes neurological ...

A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington's disease? They found that ...

Genetic mutations occur everyday in our cells, but the vast majority of them are repaired. New research finds DNA repair is not on PAR in HD cells, causing mutations to build up in people with HD.

The expansion of the polyglutamine tract alters protein conformation ... and alleviated symptoms in a mouse model of Huntington disease. [4] The authors went on to test transgenic mouse models ...

Charles River and CHDI announce an extension of their partnership, having worked together since 2005 to expedite therapies for Huntington's disease.

Amy is adopted and has no contact with her biological parents, which has made it harder for her to trace the origins of her ...

Huntington's disease is a genetic disorder that usually appears in adulthood, causing the progressive breakdown of nerve cells in the brain. However, a West Texas family traveled all the way to ...

BUFFALO, N.Y. — A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington’s disease?

How exactly does a mutated huntingtin protein (HTT) cause Huntington’s disease? They found that HTT is something like a traffic controller inside neurons, moving different cargo along neuronal ...