For the antihistamine desloratadine, in vitro studies have revealed it to be a highly potent H 1-receptor antagonist and inhibitor of inflammatory mediators. Animal models with desloratadine have ...

There are two different types of histamines: H-1 receptor antagonists and H-2 receptor antagonists. Typically, antihistamines that treat H-2 receptor antagonists treat gastrointestinal symptoms.

We therefore narrowed our studies to a selected group of biogenic amine receptors that have been most closely linked with weight gain or loss. Comparison of Weight Gain with Selected Biogenic ...

In the following section, the various methods used to evaluate antihistamines illustrate the developmental process for evaluating the efficacy of the H 1-receptor antagonist desloratadine.