For the antihistamine desloratadine, in vitro studies have revealed it to be a highly potent H 1-receptor antagonist and inhibitor of inflammatory mediators. Animal models with desloratadine have ...

Antihistamine drugs work by preventing histamine from attaching to H1 receptors. Researchers have learned something new about these receptors and other medically important proteins. Itchy eyes ...

There are two different types of histamines: H-1 receptor antagonists and H-2 receptor antagonists. Typically, antihistamines that treat H-2 receptor antagonists treat gastrointestinal symptoms.

Simultaneous pre-treatment with antihistamines that block both the H1 and H4 antihistamine receptors suppressed the gastrointestinal symptoms of food allergy in mice, according to researchers at ...

Meclizine, a histamine H1 receptor antagonist, is used to treat acute vertigo but can cause sedation, impaired motor function and other side effects. These adverse events are particularly ...

In the following section, the various methods used to evaluate antihistamines illustrate the developmental process for evaluating the efficacy of the H 1-receptor antagonist desloratadine.