Acid reducing medicines from the group of proton pump inhibitors (PPIs) are best-selling drugs that prevent and alleviate stomach problems. PPIs are activated in the acid-producing cells of the ...
Figure 1: Architecture and function of a resting channel. Figure 3: Collapse of the acidic pocket initiates channel activation. To elucidate the contributions of acidic pocket collapse to pH-dependent ...
Acid reducing medicines from the group of proton pump inhibitors (PPIs) are best-selling drugs that prevent and alleviate stomach problems. PPIs are activated in the acid-producing cells of the ...