Thought LeadersMaxim Molodtsov, Ph.D. Randhir Kumar, Ph.D. From optical trapping experiments to insights into molecular force generation, Dr. Maxim Molodtsov shared how his research is uncovering the ...
Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D genome architecture. The cohesin complex dynamically restructures ...
A research team at Kyoto University has discovered STAG3-cohesin, a new mitotic cohesin complex that helps establish the unique DNA architecture of spermaotogonial stem cells (SSCs), the stem cells ...
Stem cells have great applications in regenerative medicine. While transcription factors traditionally dominate fate determination research, recent 3D genomics reveals chromatin topology’s critical ...
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A new role for DNA loops in repairing genetic damage
When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...
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