Japanese researchers used CRISPR-Cas9 to remove the extra chromosome 21 from cells in a lab. It’s a real breakthrough — but ...

Scientists in Japan have used gene-editing technology to remove the extra chromosome responsible for Down syndrome, at least in lab-grown human cells. Down syndrome occurs when a person is born with ...

Conservation of genomic sequences between species indicates regions of functional importance, containing protein-coding gene, non-coding genes or regulatory elements. In the December 5 Nature, ...

A research team led by geneticist Jeannie Lee at Harvard Medical School, cell biologist Jeanne Lawrence at UMass Chan Medical School, and molecular biologist Jun Jiang has used a refined version of ...

The unveiling of the DNA sequences of human chromosomes represents a new chapter in the unfolding story of genomics, but one with roots in the half-century-old field of cytogenetics. Chromosome-level ...

In 1959, French geneticist Jérôme Lejeune made a landmark discovery – Down syndrome was caused by the presence of an extra copy of chromosome 21. For over six decades since this revelation, our ...

Researchers used CRISPR-Cas9 to remove the extra chromosome 21 in Down syndrome cell cultures. Edited cells showed restored gene expression to typical levels. The findings are limited to lab-grown ...