How the proteins in our bodies bind together to form protein complexes plays a critical role in numerous cell functions—staving off diseases, for instance, or transporting ions across cell membranes.

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...

The 2020 Nobel Prize in Chemistry was awarded for the development of CRISPR/Cas9, a method also known as "gene scissors," which enables researchers to better understand how human cells function and ...

The endosomal sorting complex required for transport (ESCRT) is a multicomplex machinery comprising proteins that are conserved from bacteria to humans and has diverse roles in regulating the dynamics ...

Just as the human body relies on organs such as the heart, lungs and intestines to carry out specialized functions, cells contain organelles (‘little organs’) that carry out essential processes and ...

Selecting specific cells to be used in an investigational therapy has led to improved recovery of heart function in a new study employing a lab model for myocardial infarction, the medical term for ...

Researchers shifted the focus to the internal properties of the membrane itself, specifically its viscosity, highlighting its critical role in controlling deformation and dynamics during essential ...

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...

Senescent "zombie" cells are essential architects required to build and maintain the brain's protective barriers.

Life and death are traditionally viewed as opposites. But the emergence of new multicellular life-forms from the cells of a dead organism introduces a “third state” that lies beyond the traditional ...

Hormones coordinate different body functions by carrying messages through the bloodstream to target cells and tissues. Hormonal imbalances occur through inadequate or excess hormone synthesis, which ...