The New Orleans Saints will host the Arizona Cardinals in Week 16 on December 27, 2026 at Noon CT. on FOX. The Saints host Arizona in the Caesars Superdome for the second consecutive season and will look to get revenge after the team opened the 2025 season against the Cardinals in a down-to-the-wire 20-13 Saints defeat.

Yohel Pozo ended the game with his first hit in seven pinch-hit at-bats this season, and the St. Louis Cardinals beat I-70 rival Kansas City 5-4 in 11 innings to set off a celebration among about 100