Genes are responsible for many cases of macrocephaly. A doctor may diagnose benign familial macrocephaly in an infant if they have a large head and a family history of larger-than-average head sizes.

Benign familial neonatal convulsions (BFNC) is a rare autosomal inherited epilepsy. We studied the KCNQ2 coding region in a large, four-generation, Italian family with BFNC. A missense mutation ...