Benadryl (diphenhydramine) and alcohol are both central nervous system (CNS) depressants. Taking them together can worsen side effects like drowsiness and difficulty with cognitive tasks. If you’re ...

Taking Benadryl with alcohol may intensify side effects such as sleepiness, dizziness, and confusion, making activities like driving dangerous. While there are no formal reports of interactions ...

Benadryl can cause certain side effects, some of which are more common than others. These side effects may be temporary, lasting a few days to weeks. However, if the side effects last longer than that ...