Microglia, the immune cells that protect the brain, are thought to maintain a healthy brain environment by removing unwanted substances through dynamic remodeling of the actin cytoskeleton, the cell's ...

Actin, traditionally associated with the cytoskeleton, also assembles within the nucleus in response to developmental cues, stress and signalling pathways. Nuclear actin exists in monomeric (G-actin) ...

A tiny chemical modification on one of the most abundant and important proteins in cells, actin, has long been somewhat mysterious, its function not fully understood, but scientists have now taken a ...

Over the last several years the identification and functional characterization of the motor proteins actin and myosin in the nucleus has initiated a change in the view of nuclear processes. It is now ...

Our skin and mucous membranes are protected by epithelial cells. This barrier tissue performs its function thanks to specialized structures called junctions. They ensure cell cohesion and regulate ...

Actin itself is a flexible molecule, which explains why various flavonoids can bind to actin in a very similar way but nevertheless produce effects that range from inhibition to stimulation. Flexible ...

Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin. The actin filament is a double-stranded helical structure ...

Spread the loveRecent research has uncovered a critical balance between nucleating and elongating actin filaments essential for the deformation of protein condensates into high aspect ratio structures ...

Historically, actin research at different levels of biological organization has developed into separate fields such as in vitro actin biochemistry, biophysics and cell biology. Biochemists, cell ...