Angel Martinez and Jose Ramirez hit back-to-back home runs in the first inning in support of right-hander Slade Cecconi, who recorded a career-high nine strikeouts to lead the Cleveland Guardians to a 4-2 win over the host Houston Astros on Wednesday and a three-game series sweep.

Houston Astros center fielder Jake Meyers left the field minutes before first pitch Wednesday assisted by a team trainer due to an apparent injury. Meyers had missed Houston's past two games with what the team termed right calf tightness.